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BackTable / MSK / Podcast / Episode #59
Minimally Invasive Bone Grafting & Orthopedic Innovation
with Dr. Jim Marino
More often than not, a surgical innovation is not the result of an overnight success, but rather the result of iterative improvements on a tool or technique that leads to better outcomes. In this episode of the BackTable MSK Podcast, we interview Dr. Jim Marino, a retired orthopedic surgeon and prolific medtech innovator. Dr. Marino gives us an inside look at his extensive career, detailing his role in orthopedic device innovation and the trials and tribulations that he faced along the way.
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BackTable, LLC (Producer). (2024, October 1). Ep. 59 – Minimally Invasive Bone Grafting & Orthopedic Innovation [Audio podcast]. Retrieved from https://www.backtable.com
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Podcast Contributors
Dr. Jim Marino
Dr. Jim Marino is a retired orthopedic surgeon and medical device innovator.
Dr. Jacob Fleming
Dr. Jacob Fleming is a diagnostic radiology resident and future MSK interventional radiologist in Dallas, Texas.
Synopsis
Having trained in an era where joint arthroscopy was emerging, Dr. Marino had a vision to build devices for minimally invasive spine surgery that paralleled developments in peripheral joint surgery. Alongside venture capitalists, he founded the company NuVasive, and eventually Trinity Orthopedics. He discusses the COREX device, a percutaneous autologous bone harvester that rivals the use of biologics. COREX maintains the gold standard of using cancellous bone grafts and significantly decreases donor site pain. Applications for this device started with bone grafting for spinal fusion surgery, but are now expanding to foot and ankle procedures.
Throughout this episode, Dr. Marino also shares valuable advice for aspiring physician innovators on maintaining a clinical practice during the entrepreneurship journey and balancing patient safety with innovative practices.
Timestamps
00:00 - Introduction
14:34 - Reflections on Spine Innovation
25:03 - Clinical and Radiographic Evaluation
31:50 - Founding NuVasive: From Ideas to Reality
43:28 - Minimally Invasive Bone Grafting with COREX
1:00:06 - Future Applications of COREX
01:10:21 - Advice for Aspiring Physician Innovators
Resources
NuVasive:
https://www.nuvasive.com/
COREX Minimally Invasive Bone Harvester:
https://trinityorthodevice.com/
YODA Project for rhBMP-2 safety and efficacy :
https://yoda.yale.edu/about/data-holders/medtronicrhbmp-2/
Seattle Science Foundation YouTube:
https://www.youtube.com/channel/UChIIig54yF9aQYvpWGe1DPg
Disclaimer: The Materials available on BackTable.com are for informational and educational purposes only and are not a substitute for the professional judgment of a healthcare professional in diagnosing and treating patients. The opinions expressed by participants of the BackTable Podcast belong solely to the participants, and do not necessarily reflect the views of BackTable.
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