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BackTable / VI / Podcast / Episode #353
MicroCT for PAD: What You Need to Know
with Dr. John Rundback
In this episode, host Dr. Sabeen Dhand interviews Dr. John Rundback about analysis of arterial calcifications using microCT.
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BackTable, LLC (Producer). (2023, August 7). Ep. 353 – MicroCT for PAD: What You Need to Know [Audio podcast]. Retrieved from https://www.backtable.com
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Podcast Contributors
Dr. John Rundback
Dr. John Rundback is a practicing Vascular Interventional Radiologist at AIVS LLP in the New York City area.
Dr. Sabeen Dhand
Dr. Sabeen Dhand is a practicing interventional radiologist with PIH Health in Los Angeles.
Synopsis
Dr. Rundback starts by describing the basic differences between microCT and current imaging techniques. MicroCT is a non-destructive imaging method where the x-ray source is stationary but the subject is on a rotating stage. This method can create 3D imaging with a 3 to 5 micron resolution. On the other hand, in traditional CT imaging, the subject is stationary and the x-ray source rotates, which gives a 3 to 5 millimeter resolution.
Then, the episode shifts to a discussion on Dr. Rundback’s recent study, in which he used microCT to evaluate the treatment effect of medial arterial calcification in below knee interventions after Auryon laser atherectomy. For this study, arteries were dissected out of cadavers with cardiac risk factors. These artery segments were then subject to different energies from the Auryon laser. MicroCT was performed before and after the procedure to analyze the degree of calcification. These trials have shown that atherectomy using the Auryon laser could increase compliance of the treated arteries. MicroCT has also helped expand knowledge about different types of calcification and how atherectomy differentially impacts them.
Resources
Treatment effect of medial arterial calcification in below-knee after Auryon laser atherectomy using micro-CT and histologic evaluation:
https://pubmed.ncbi.nlm.nih.gov/37400346/
Auryon Atherectomy Device:
https://www.angiodynamics.com/product/auryon/
Transcript Preview
Micro-CT is not a miniaturized CT scanner. As a matter of fact, it's sort of the opposite in the sense that obviously in a CT scanner, the subject is stationary and the image or the fluorosource or the X-ray source rotates in the gantry, and obviously, various technologies around that. In micro-CT, the X-ray source is stationary, but the object is rotating. So that's how you get the three-dimensional perspective. The difference is that, unlike a CAT scanner, which you get maybe 3 millimeter, if you really want to get thin cuts, 1 millimeter resolution, the resolution from micro-CT, which is a non-destructive imaging method, is in the range of 3 to 5 microns, with the Nikon device we use, and in some cases, as low as 1 micron. It's really a microscopic evaluation of the tissues.
AngioDynamics and Auryon are trademarks and/or registered trademarks of AngioDynamics, Inc., an affiliate or subsidiary.
Disclaimer: The Materials available on BackTable.com are for informational and educational purposes only and are not a substitute for the professional judgment of a healthcare professional in diagnosing and treating patients. The opinions expressed by participants of the BackTable Podcast belong solely to the participants, and do not necessarily reflect the views of BackTable.
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