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ALBI Score Calculator

The ALBI score (Albumin-Bilirubin score) is a valuable tool for assessing liver function in patients with chronic liver disease or hepatocellular carcinoma. Unlike traditional scoring systems, such as the Child-Pugh score, the ALBI score relies solely on objective laboratory values, making it a simpler and more precise measure. BackTable’s ALBI score calculator simplifies the process by automating calculations and minimizing errors. Clinicians can input the required parameters (bilirubin and albumin levels) into the calculator, and it instantly provides the ALBI score.

Bilirubin (mg/dL):

Albumin (g/dL):

Calculate

Value

What is an ALBI Score?

The ALBI score evaluates liver function by incorporating two critical laboratory parameters: serum albumin (g/L) and bilirubin levels (μmol/L). It uses the formula:

ALBI = (log10 bilirubin × 0.66) + (albumin × −0.085)

This scoring method eliminates subjectivity by relying solely on measurable values, allowing clinicians to make more consistent assessments. By categorizing patients into grades, the ALBI score provides a clear picture of liver function. This has significant implications for patient care, particularly in treatment planning for hepatocellular carcinoma and other liver-related conditions.

ALBI Score Interpretation

The ALBI score is categorized into three grades, each with distinct clinical implications:

Grade: 1
• ALBI Score <= -2.60
• Median Survival: 18.5 - 85.6 months
• Best prognosis

Grade: 2
• ALBI Score > -2.6 to <= –1.39
• Median Survival: 5.3 - 46.5 months

Grade: 3
• ALBI Score >= -1.39
• Median Survival: 2.3 - 15.5 months
• Worst prognosis

These grades are critical in guiding treatment decisions and assessing patient prognosis. For example, patients with a Grade 1 score may tolerate aggressive treatments better than those with Grade 3.

ALBI Score Clinical Applications

The ALBI score is widely used in clinical settings for:
• Assessing liver function: It provides a reliable measure of hepatic reserve in patients with chronic liver disease.
• Predicting outcomes: Particularly in hepatocellular carcinoma, the ALBI score helps estimate survival rates and response to treatments.
• Treatment planning: By categorizing patients based on liver function, clinicians can tailor interventions to minimize risks and optimize outcomes.

Learn more on the BackTable VI Podcast

BackTable is a knowledge resource for physicians by physicians. Get practical advice on the ALBI Score Calculator and how to build your practice by listening to the BackTable VI Podcast, reading exclusing BackTable Articles, and following the work of our Contributors.

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References

[1] Pugh, R. N. H., et al. "Prognostic factors in cirrhosis." Gut, 1973.
[2] Johnson, P. J., et al. "Assessment of liver function in patients with hepatocellular carcinoma: a new evidence-based approach—the ALBI grade." Journal of Clinical Oncology, 2015.
[3] Chan, A. W. H., et al. "Development of a novel ALBI-based nomogram for hepatocellular carcinoma prognosis." Clinical Cancer Research, 2016.
[4] Bruix, J., et al. "Management of hepatocellular carcinoma." Hepatology, 2011.
[5] Kudo, M., et al. "ALBI grade and prognosis in hepatocellular carcinoma." Liver Cancer, 2017.

Disclaimer: The Materials available on BackTable.com are for informational and educational purposes only and are not a substitute for the professional judgment of a healthcare professional in diagnosing and treating patients. The opinions expressed by participants of the BackTable Podcast belong solely to the participants, and do not necessarily reflect the views of BackTable.